Vitex agnus castus causes a decrease in prolactin, which leads to a reversal of LH
suppression Increasing progesterone levels and Reducing symptoms of PMS.
The GLA omega-6 fatty acids present in evening primrose oil can help to regulate
hormone levels during the cycle, providing a steadier emotional balance & also
reduce hormonal acne.
Wheat germ has anti-inflammatory, sedative, antidepressant, and soothing
properties and is rich in vitamins E, B12, B6, magnesium, zinc, and calcium.
Magnesium supplementation can reduce the severity of menstrual pain and its
associated symptoms by decreasing the level of prostaglandins.
Clinical comparison of Vitex agnus, Evening Primrose and vitamin E on severity of premenstrual
syndrome.
Clinical study on 210 women with PMS, Vitex agnus, Evening Primrose and vitamin E can reduce
severity of premenstrual syndrome, but therapeutic effect of Vitex agnus is more than Evening
Primrose and Vitamin E.
Clinical efficacy comparison of Vitex+ Magnesium+ Vitamin B6 combination with standard therapy
and stand alone on severity of PMS
Clinical study involving 64 participants with varied severity of PMS;
There is significant improvement in QOL with Nutraceutical (Vitex+ Magnesium+ Vitamin B6) or
Nutraceutical + Standard therapy in 90 days (p<0.05).
Clinical study to compare effect of Magnesium and vitamin B6 Vs. Placebo on PMS
Clinical trial was conducted on 126 women with PMS, demonstrated the positive effects of
Magnesium and vitamin B6 on reduction of all premenstrual syndrome symptoms as compared to
placebo.