The Heart performs a particular workload of pumping blood to every nook and corner of the body ... this is nonstop throughout our life! When the heart fails to carry out this pumping workload (totally or to some extent) is called as Heart Failure (HF). It doesn't mean a total collapse always; many patients live a full life (with some compromise) through medication and other lifestyle modifications!

There are a few types of HF. When the left ventricle (LV) becomes unable to pump normally and ejected blood gets reduced, it is called as 'Reduced ejection fraction or HFrEF" (also known as systolic HF). Whereas, when the LV cannot relax properly due to muscle stiffness or so and gets incompletely filled-up with blood, it is called as 'Preserved ejection fraction or HFpEF" (also known as diastolic HF). Congestive HF (CHF) is a situation when blood fails/slows-down to return to the heart through the veins causing congestion across the body. This requires timely medical intervention.

'The burden of HF in India appears high and estimates of prevalence range from 1.3 million to 4.6 million, with an annual incidence of 491 600–1.8 million. However, reliable data is lacking because of inadequate surveillance systems.¹

“Oral administration of CoQ10 has been observed to raise the endogenous level of CoQ10 in plasma. In agreement with studies, the plasma level of CoQ10 can be proposed as a predictor of the mortality in HF patients. Besides the functions of CoQ10 mentioned before, one of the actions of CoQ10 in HF is the inotropic one. It improves cardiac output by the rise of heart’s contractile force”²

Curcumin is a natural product derived from turmeric that appears to have cardiovascular benefits through a number of mechanisms. In this review, we have assessed the mechanisms by which curcumin may exert its effects in different models of heart failure and show that it has promise as a complementary treatment in heart failure³